Earlier Real Madrid Beaten 2-1 at Valencia in La Liga last weekend and 2-0 at Atletico Madrid in a King's Cup last 16 first leg in midweek, Real take lead when Cristiano Ronaldo set up James Rodriguez to score in 12th minute. Gareth Bale free kick over the wall and into the net off a post to make it 2-0 in the 28th minute. Real remained in control and substitute Nacho clipped home a third goal.
The victory stretched Real's lead over second-placed Barcelona to four points. The Catalans entertain champions Atletico, who are level with their hosts on 38 points, on Sunday.
Today things went well," Real play maker Isco told Spanish television. "We are happy with the victory and to win again and get back on track.
"We have to continue the same way in the league and if the other teams slip up then so much the better."
Ronaldo failed to score at home in La Liga for the first time in more than 15 months, ending a run of 17 straight games on target at the Bernabeu. Ronaldo the most goals (26) and the most assists (nine) in the league this term.
"Cristiano Ronaldo seems the same as ever to me," said Real coach Carlo Ancelotti. "He is in great shape physically and playing for the team. He didn't score but the assist for the opening goal was fantastic."